A thorough review of PT-141 may interest researchers. A synthetic peptide called PT-141 has been suggested to significantly impact arousal and mating/sexual behaviors via activating specific brain receptors. In this review, we will take a look at the most examined PT-141 scenarios and see how they compare in studies related to:
- Libido
- Erectile function
- Hunger
In addition to finding out where to get high-quality PT-141 for reference, readers will also find in-depth information on the peptide’s hypothesized mechanisms if action and possible functions.
PT-141 Peptide: Mechanism of Action
PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide that appears to mimic the action of the pituitary gland’s major hormone, α melanocyte-stimulating hormone (alpha-MSH). Because of its interactions with several melanocortin receptors (MCRs), alpha-MSH influences various physiological functions. Except for the adrenal gland-specific MC2R, PT-141 has been hypothesized to activate all five known MCRs. The main alleged impacts of PT-141 activating MCR receptors are summarized below:
- Tanning and skin and hair/fur pigmentation may result from increased melanin synthesis brought about by interactions with MC1R in these tissues.
- When MC3R and MC4R are activated, they may greatly influence mating and sexual behavior in the organism.
- Controlling food intake and energy balance: MC3R and MC4R are considered to be critical in these processes. For instance, MC4R activation may lead to decreased…
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New York City Immigrant Heritage Celebration 2024
The Mayor’s Office of Immigrant Affairs kicks off the 20th annual Immigrant Heritage Week with a campaign Celebrating the City of Immigrants, honoring long time immigrant New Yorkers and recently arrived immigrants. This year, we celebrate the resilience and determination of past immigrants who built longstanding support…
Bronx Calling: The Sixth AIM Biennial – Part Two
All are invited to join us in celebrating the opening of Bronx Calling: The Sixth AIM Biennial – Part Two at The Bronx Museum on Friday, April 12, 2024, between the hours of 7:00 p.m. and 9:00 p.m.
The party is free to attend, but please let…
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By Jonas BronckREAL ESTATE
NEWS
Scoring A Goal For Affordable Housing
By Jonas BronckDespite Sharpest Case Increase, The Bronx Remains Least Active Foreclosure Market In NYC
By Jonas BronckNew York City To Create Tens Of Thousands Of Affordable Homes
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By Jonas Bronck
On Monday, December 18, 2023, at approximately 1121, hours, New York City Police Department (NYPD) officers responded to a 911 call for an aided child at 240 E. 175th Street, within the confines of the 46th Precinct in the Bronx.
Upon arrival, officers observed a 5-year-old male and a 5-year-old female, unconscious and unresponsive, inside an apartment at the location.
EMS responded and pronounced the aided children deceased at the scene.
The Office of the Chief Medical Examiner deemed the cause of both deaths as murder.
Following proper family notification, the victims have been identified as indicated.
Victims:
George & Gianna Kantanka
240 E. 175 Street
Bronx, NY 10457
Pursuant to an ongoing investigation, the following 42-year-old female individual was arrested and charged on Thursday, April 11, 2024, at 1435 hours, within the confines of the 46th Precinct.
Arrested:
Gloria Asamoah
240 E. 175 Street
Bronx, NY 10457
Charges:
- murder;
- manslaughter.
The investigation remains ongoing.
All charges are merely accusations and all defendants are presumed innocent until and unless proven guilty.
Anyone with information related to this incident is asked to call the NYPD‘s Crime Stoppers hotline at 1–800–577–TIPS (8477) or for Spanish, 1–888–57–PISTA (74782). The public can also submit their tips by logging onto the Crime Stoppers‘ website or by texting their tips to 274637 (CRIMES) then enter TIP577.
All tips will be kept strictly confidential.
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& PUNISHMENT
Schward Bee, 31, Arrested For The Murder Of Stefon Barnes, 29
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By Jonas BronckEditorial
You should know that in one of his first public appearances, after having resigned as Governor for New York State, Andrew Cuomo will be visiting the South Bronx. His visit to the Bronx is to meet with Members of “The New York Hispanic Clergy Organization”, which I preside over.
As you know, last summer Governor Cuomo resigned, when he was accused and practically abandoned by all his friends, politicians, and community groups, whom he had helped in the past. These so-called friends, and groups that were all too happy to kiss his ring, joined the “cancel culture” environment, that plaques us all, without due process, they washed their hands with a dismissive attitude, sending the message “Crucify him, crucify him”.
Several courts and judges have dismissed the allegations of “sexual harassment” against Governor Cuomo. With this episode behind him, Governor Cuomo has begun to visit and make public appearances by visiting different faith-based organizations and community groups.
It is very important for you to know that Governor Cuomo’s first public visit was to “God’s Battalion of Prayer Temple” in East Flatbush, Brooklyn on Sunday March 06, 2022. His next planned visit is to the “New York Hispanic Clergy Organization” in the South Bronx.
You should also know that in a recent poll, Governor Cuomo, without being a candidate nor having announced his political aspirations, has polled with just four (4) points behind Governor Kathy Hochul.
As you know, Governor Hochul was a friend and she was handpicked by Cuomo to be his Lieutenant Governor. However, she was among one of the first to throw him under the bus, in the midst of the allegations, launched against him.
I imagine that those four (4) points will evaporate very soon and Governor Hochul will have to consider asking Governor Cuomo for his support, if she wishes to be officially elected by the people to the governorship.
As President of the “New York Hispanic Clergy Organization”, I am looking forward to hosting Governor Cuomo on Thursday, March 17, 2022. We welcome him to the South…
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EDUCATION
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The Patriot Scholarship 2024
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On the morning of April 12, 2024, at City Hall, we spoke with Sheena Wright, First Deputy Mayor; Jose Bayona, Executive Director of the Mayor’s Office of Ethnic and Community Media; and Abby Jo Sigal, Executive Director of the Mayor’s Office of Talent and Workforce Development, regarding the Mayor’s Office Hiring Hall initiative.
Last year, the New York City (NYC) Mayor’s office and other agencies launched the Hiring Halls initiative, aimed at boosting employment opportunities in areas with high unemployment rates. These events are designed as comprehensive employment gatherings, providing job seekers with the chance to connect with municipal agencies, interview with employers, and even secure same-day job offers—all within their own neighborhoods.
Following the success and lessons learned from last year’s pilot program, NYC is now revamping its strategy and plans to hold Hiring Halls every month across the boroughs over the next few months. These events will serve as vital hubs for job seekers to engage with a variety of employers and training providers, including organizations like the City University of New York (CUNY) and their English language programs.
With NYC experiencing the highest private sector employment in its history, boasting a job market of 4.7 million, the initiative aims to refocus efforts on high-unemployment areas such as Harlem, Brownsville, Southeast Queens, the South Bronx, and others in a broader effort to stimulate local economies and combat joblessness.
Today Is Tax Day
The New York State Department of Taxation and Finance today highlighted last-minute filing resources for taxpayers who have yet to submit their personal income tax returns. The deadline to file and pay any taxes owed is 11:59 p.m. Eastern Daylight Time (EDT) Monday, April 15, 2024.
TL;DR: Key Points on the New York Rangers’ Playoff Potential
- The Rangers lead the Metropolitan Division with a 45-20-4 record and 94 points, demonstrating their dominance in the NHL.
- They rank 4th in goal differential at +44, reflecting their ability to outscore opponents effectively.
- Their 5-on-5 play is solid, with a near-even expected goals ratio, indicating balanced offensive and defensive capabilities.
- The team has matched a franchise record with 10 consecutive wins, showcasing their current form and momentum.
- Artemi Panarin stands out with 94 points, ranked 5th in the NHL, supported by significant contributions from Chris Kreider, Mika Zibanejad, Vincent Trocheck, and Adam Fox.
- Goalie Igor Shesterkin has a strong record, further solidifying the team’s defensive strength.
- Playoff odds are favorable, with a 100% chance of making the playoffs and around a 20% chance of winning the Stanley Cup, according to various models.
Team Performance Overview
The New York Rangers are leading the Metropolitan Division with an impressive 45-20-4 record, amassing 94 points. This places them not only at the top of their division but also positions them as a formidable team across the NHL, where they stand with a fourth-place ranking in goal differential at +44.
At 5-on-5, the Rangers boast a 49.8% Corsi For percentage. This statistic, which measures shot attempt differential, underscores their…
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